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Haemorrhoids

GMJ News knowledge hub · last reviewed September 2026 · Georgian Medical Journal

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Haemorrhoids — symptomatic enlargement and distal displacement of the normal anal cushions — are among the most common anorectal conditions worldwide, affecting an estimated 4-5% of adults symptomatically with far higher rates on examination, and are strongly associated with constipation, prolonged straining, low dietary fibre, pregnancy and prolonged sitting (WHO). The single most important clinical principle is that rectal bleeding must never be attributed to haemorrhoids without excluding colorectal malignancy in patients over 40, those with alarm features (weight loss, altered bowel habit, iron deficiency anaemia, family history) or those whose bleeding does not resolve with treatment — misattribution of cancer bleeding to haemorrhoids is a recurrent and well-documented cause of delayed colorectal cancer diagnosis and successful medicolegal claims.

Key messages

NEVER attribute rectal bleeding to haemorrhoids without excluding cancer
The single most important clinical rule. Rectal bleeding must not be attributed to haemorrhoids in: any patient over 40-50 (threshold varies by guideline and local colorectal cancer incidence); anyone with alarm features (unintentional weight loss, altered bowel habit, iron deficiency anaemia, abdominal or rectal mass, family history of colorectal cancer or IBD); or anyone whose bleeding persists despite treatment. Misattribution of colorectal cancer bleeding to visible haemorrhoids is a well-documented, recurrent cause of delayed cancer diagnosis and of successful medicolegal claims. The presence of haemorrhoids on examination does not exclude a synchronous proximal cancer.
Goligher grading determines treatment
Grade I: bleed but do not prolapse — conservative management (fibre, fluids, avoid straining) ± topical agents. Grade II: prolapse on straining, reduce spontaneously — conservative + office procedures (rubber band ligation first-line). Grade III: prolapse and require manual reduction — rubber band ligation or surgery. Grade IV: irreducibly prolapsed — surgery (haemorrhoidectomy). External haemorrhoids and thrombosed external haemorrhoids are graded separately and managed differently.
Rubber band ligation is the most effective office procedure
Rubber band ligation (RBL): bands applied to the haemorrhoidal pedicle ABOVE the dentate line (insensate — critical point: banding below the dentate line causes severe pain and is a technical error). Most effective non-surgical intervention for grade I-III internal haemorrhoids; superior to sclerotherapy and infrared coagulation in meta-analysis; can be repeated. Complications: pain (usually mild, from banding too low); delayed bleeding at 7-10 days when the band separates (occasionally significant); vasovagal episodes; and rarely, pelvic sepsis (a surgical emergency — presenting with severe pain, fever and urinary retention, requiring immediate assessment). Avoid RBL in anticoagulated patients and in immunosuppression.
Thrombosed external haemorrhoid — the 72-hour window
An acutely thrombosed external haemorrhoid presents as a sudden, exquisitely painful, tense purple perianal lump. If the patient presents WITHIN 72 hours of onset (pain at its peak), excision of the thrombosed haemorrhoid under local anaesthetic gives immediate and dramatic relief and reduces recurrence — this is excision, not simple incision and clot expression, which has higher recurrence. If the patient presents AFTER 72 hours (pain already improving as the clot organises), conservative management is appropriate: analgesia, stool softeners, sitz baths — the lesion resolves spontaneously over 1-2 weeks, often leaving a skin tag.
Anal fissure is the key differential — pain, not painless bleeding
Haemorrhoids characteristically cause PAINLESS bright red bleeding (blood on paper, dripping into the pan, coating rather than mixed into the stool). Severe pain during and after defaecation, often described as passing broken glass, with a small amount of bright blood, indicates ANAL FISSURE — a completely different condition. Fissure treatment: high-fibre diet, stool softeners, sitz baths, and topical vasodilators to reduce internal anal sphincter hypertonia — glyceryl trinitrate (GTN) 0.4% ointment or diltiazem 2% cream (better tolerated, less headache), for 6-8 weeks. Chronic fissure failing medical therapy: botulinum toxin injection or lateral internal sphincterotomy (highly effective but small risk of incontinence).
Fibre and defaecatory habit are the foundation — and the prevention
Conservative management underpins all treatment: soluble fibre supplementation (ispaghula/psyllium — Cochrane evidence for reduced bleeding and symptoms), adequate fluid, and — critically — behavioural change: do not strain; do not sit on the toilet for prolonged periods (reading, phone use — a major and under-addressed contributor); respond promptly to the call to stool. Toilet posture with the knees elevated above the hips (a footstool) straightens the anorectal angle and reduces straining. These measures both treat existing haemorrhoids and prevent recurrence after any procedure — without them, recurrence rates after banding or surgery are high.

Key statistics

4-5%
of adults report symptomatic haemorrhoids; far higher prevalence on examination
ASCRS/ACPGBI
Never assume
rectal bleeding is haemorrhoidal without excluding colorectal cancer in at-risk patients
NICE/ASCRS
Above dentate
rubber band ligation must be applied above the dentate line — below causes severe pain
ASCRS
72 hours
window for excision of a thrombosed external haemorrhoid — after this, manage conservatively
ASCRS
Painful = fissure
severe pain on defaecation indicates anal fissure, not haemorrhoids — different treatment
ASCRS/ACPGBI
Diltiazem 2%
topical — as effective as GTN for anal fissure with substantially fewer headaches
Cochrane

Haemorrhoid treatment by Goligher grade (ASCRS guidelines)

Source: ASCRS/ACPGBI. Conservative measures underpin all grades; rubber band ligation is the most effective office procedure.

Glossary of key terms

Anal cushions and the dentate line
Anatomy
The anal cushions are normal vascular structures — submucosal arteriovenous plexuses supported by connective tissue (Treitz's muscle) — located in the left lateral, right anterior and right posterior positions. They contribute approximately 15-20% of resting anal continence pressure and are essential for fine continence of gas and liquid. Haemorrhoids are not varicose veins: they are these normal cushions that have become engorged and distally displaced through degeneration of their supporting connective tissue. This is why complete excision of all cushions impairs continence — and why treatments aim to reduce and refix rather than eradicate. The dentate (pectinate) line marks the transition from insensate visceral (columnar, above) to exquisitely sensitive somatic (squamous, below) innervation — the single most important landmark in anorectal intervention.
Goligher classification
Colorectal surgery
The standard grading of internal haemorrhoids: Grade I — bleed but do not prolapse below the dentate line. Grade II — prolapse on straining or defaecation but reduce spontaneously. Grade III — prolapse and require manual reduction. Grade IV — permanently prolapsed and cannot be reduced (includes acutely thrombosed or strangulated internal haemorrhoids). External haemorrhoids (arising below the dentate line, covered by squamous anoderm) are not included in this grading and are managed separately; skin tags are the residue of previous external thrombosis and require no treatment unless causing hygiene difficulty.
Haemorrhoidectomy techniques
Colorectal surgery
Conventional excisional haemorrhoidectomy (Milligan-Morgan open, or Ferguson closed): the most effective and durable treatment, with the lowest recurrence — but the most postoperative pain (typically 2-4 weeks). Stapled haemorrhoidopexy (PPH): excises a circumferential ring of rectal mucosa above the dentate line and repositions the cushions; less immediate pain but higher recurrence and prolapse rates, and rare but severe complications (rectovaginal fistula, pelvic sepsis, rectal stenosis) — NICE and several national bodies have restricted its use. Haemorrhoidal artery ligation with recto-anal repair (HALO/THD, Doppler-guided): less pain than excision, but the HubBLe trial (Lancet 2016) found higher recurrence than rubber band ligation at 1 year and no cost-effectiveness advantage. Excisional haemorrhoidectomy remains the gold standard for grade III-IV disease.
Anal fissure — pathophysiology and treatment
Colorectal
An anal fissure is a longitudinal tear in the anoderm, most commonly in the posterior midline (approximately 90%; anterior midline in 10%, more common in women postpartum). Pathophysiology: internal anal sphincter hypertonia → reduced anodermal blood flow → the posterior midline is a relative watershed area → ischaemia prevents healing → pain causes further sphincter spasm (a vicious cycle). Treatment therefore targets sphincter relaxation: topical GTN 0.4% or diltiazem 2% for 6-8 weeks (diltiazem preferred — equally effective, far fewer headaches); plus stool softening and sitz baths. Refractory chronic fissure: botulinum toxin injection into the internal sphincter (temporary chemical sphincterotomy) or lateral internal sphincterotomy (highest healing rate, approximately 95%, but carries a small risk of flatus or faecal incontinence — counsel carefully, particularly in women with obstetric sphincter injury). IMPORTANT: fissures that are lateral, multiple, irregular or painless are NOT typical — investigate for Crohn's disease, tuberculosis, HIV, syphilis, or anal carcinoma.
Haemorrhoids in pregnancy
Obstetrics
Very common — driven by increased circulating volume and progesterone-mediated venous laxity, gravid uterine pressure on pelvic veins, constipation, and the acute strain of the second stage of labour. Management is predominantly conservative: dietary fibre and fluids; bulk-forming laxatives (ispaghula) and macrogol are safe in pregnancy; topical preparations containing local anaesthetic and low-potency corticosteroid for short-term symptomatic relief; sitz baths; avoid prolonged standing. Most postpartum haemorrhoids and acute thromboses regress substantially within weeks of delivery. Surgery is generally deferred until at least 3-6 months postpartum unless there is strangulation or intractable bleeding — allowing spontaneous improvement and avoiding unnecessary intervention.
When to refer urgently
NICE/Primary care
Urgent lower GI investigation (suspected cancer pathway) is required for: rectal bleeding with a change in bowel habit; rectal bleeding in patients above the local age threshold (commonly 40-50) without an obvious anorectal cause; iron deficiency anaemia; unintentional weight loss; abdominal or rectal mass; persistent bleeding despite treatment of an apparent anorectal cause. Emergency surgical assessment is required for: strangulated or gangrenous prolapsed haemorrhoids (severe pain, necrotic mucosa); severe post-banding pain with fever or urinary retention (possible pelvic sepsis — rare but life-threatening); and profuse bleeding causing haemodynamic compromise.

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Related health topics

Colorectal cancer (must exclude)Constipation and strainingIBD (bleeding differential)Haemorrhoids in pregnancyPelvic floor and continenceIron deficiency from chronic bleeding

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