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Otitis Media

GMJ News knowledge hub · last reviewed September 2026 · Georgian Medical Journal

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Otitis media — inflammation of the middle ear — is one of the most common diseases of childhood, with acute otitis media (AOM) accounting for an enormous share of paediatric antibiotic prescriptions globally, and chronic suppurative otitis media (CSOM) affecting an estimated 65-330 million people worldwide, predominantly in low-income settings, where it is a leading and largely preventable cause of permanent hearing loss and consequent educational disadvantage (WHO). Most acute otitis media in otherwise healthy children over two years resolves spontaneously, and delayed or back-up antibiotic prescribing is the guideline-endorsed default — with immediate antibiotics reserved for children under six months, those under two years with bilateral disease, systemic illness, otorrhoea, immunocompromise or craniofacial abnormality — while otitis media with effusion (“glue ear”), the commonest cause of acquired childhood hearing loss, warrants three months of watchful waiting with formal hearing assessment before considering grommets, and the emergence of post-auricular swelling with a protruding pinna signals mastoiditis requiring emergency admission.

Key messages

Delayed or back-up antibiotic prescribing is the default in acute otitis media
Most acute otitis media (AOM) in otherwise healthy children over two years resolves spontaneously within a few days. NICE, AAP and most national guidelines endorse a no-antibiotic or delayed (back-up) prescription strategy with adequate analgesia as the default — the parent uses the prescription only if the child is not improving after 3 days or deteriorates. Given the enormous volume of paediatric AOM consultations, this is one of the largest antimicrobial stewardship targets in child health.
Immediate antibiotics for the specific higher-risk groups
Immediate antibiotics ARE indicated for: children under 6 months; children under 2 years with BILATERAL acute otitis media; any child with otorrhoea (discharge from a perforated drum); systemically unwell children or those with signs of serious illness; immunocompromise; craniofacial abnormality including cleft palate; cochlear implants; and children who deteriorate or fail to improve on a delayed strategy. First-line is amoxicillin (high dose in settings with pneumococcal resistance), with amoxicillin-clavulanate for treatment failure or recent antibiotic exposure.
Analgesia is the treatment that actually relieves the child
Pain is the dominant symptom and the reason families attend, yet it is routinely under-treated while attention focuses on the antibiotic decision. Regular paracetamol and ibuprofen, given at adequate dose and at fixed intervals rather than as-needed, provide the relief that matters in the first 48-72 hours — during which antibiotics make little difference regardless. Explicitly framing analgesia as "the treatment" rather than as an alternative to treatment substantially improves parental acceptance of a delayed antibiotic strategy.
Otitis media with effusion — 3 months watchful waiting, then hearing assessment
OME ("glue ear") — fluid in the middle ear without acute infection — is the commonest cause of acquired hearing loss in childhood. Most resolves spontaneously. Guidance: a period of watchful waiting of approximately 3 months with formal hearing assessment (audiometry and tympanometry) at the end, before considering intervention. Grommets (tympanostomy tubes) are indicated for persistent bilateral OME with significant hearing loss and functional impact on speech, language, learning or behaviour. Autoinflation (Otovent balloon) has modest evidence. Antibiotics, antihistamines, decongestants and intranasal steroids are NOT effective for OME and should not be used.
Chronic suppurative otitis media — a leading preventable cause of hearing loss globally
CSOM — persistent middle ear discharge through a perforated tympanic membrane for more than 2 weeks — affects an estimated 65-330 million people worldwide, overwhelmingly in low-income settings, and is a major and preventable cause of permanent hearing loss with consequent educational and economic disadvantage. WHO evidence supports aural toilet (dry mopping) plus TOPICAL antibiotics — which achieve far higher local concentrations than systemic therapy — as the mainstay. Topical quinolones (ciprofloxacin, ofloxacin) are preferred over aminoglycoside drops because of cochleotoxicity risk through a perforation.
Mastoiditis and intracranial complications — the emergency presentations
Acute mastoiditis: post-auricular swelling, redness and tenderness with the pinna pushed forward and downward, loss of the post-auricular sulcus, and systemic illness. This is an emergency requiring admission, IV antibiotics, contrast CT and often surgery (cortical mastoidectomy, myringotomy). Other complications to recognise: facial nerve palsy; labyrinthitis; petrositis (Gradenigo's syndrome — otorrhoea, deep retro-orbital pain and abducens palsy); lateral sinus thrombosis; meningitis; and intracranial abscess. Cholesteatoma — keratinising squamous epithelium in the middle ear, presenting with painless foul-smelling discharge and an attic or marginal retraction pocket — is progressive, erosive and requires surgical management.

Key statistics

Delayed Rx
back-up antibiotic prescribing is the guideline default for uncomplicated AOM in children over 2
NICE/AAP
65-330M
people worldwide affected by chronic suppurative otitis media
WHO
<2 years
with BILATERAL AOM, or any child with otorrhoea — immediate antibiotics indicated
NICE/AAP
3 months
watchful waiting with formal hearing assessment before grommets for OME
NICE/AAO-HNS
Topical
quinolone drops preferred in CSOM — higher local concentration; avoid aminoglycosides
WHO/Cochrane
Post-auricular
swelling with protruding pinna = mastoiditis = emergency admission
AAO-HNS/ENT UK

Otitis media — intervention effectiveness by condition (NICE/AAP/Cochrane)

Source: NICE/AAP/Cochrane. Analgesia and topical therapy dominate; antibiotics have no role in OME.

Glossary of key terms

Otoscopic findings
ENT/Examination
Acute otitis media: a bulging, opaque, erythematous tympanic membrane with loss of the normal light reflex and landmarks — BULGING is the most specific single sign; erythema alone is unreliable, since a crying child's drum is often red. Otitis media with effusion: a retracted or neutral, dull, amber or grey drum, sometimes with visible fluid level or air bubbles, and reduced mobility — pneumatic otoscopy or tympanometry (type B flat trace) confirms. Perforation with otorrhoea: visible defect with discharge. Cholesteatoma: an attic or posterosuperior marginal retraction pocket filled with white keratin debris, often with granulation and foul-smelling discharge — this is the appearance that must never be dismissed as simple chronic infection.
Tympanometry
Audiology
A quick, objective measure of middle ear function that complements otoscopy and is particularly valuable in young children. Type A: normal middle ear pressure and compliance. Type B: a flat trace with normal ear canal volume — indicating middle ear effusion (glue ear); with LARGE canal volume it instead indicates a perforation or patent grommet. Type C: significantly negative middle ear pressure — Eustachian tube dysfunction, often preceding or following effusion. Tympanometry does not measure hearing and must be paired with age-appropriate audiometry — visual reinforcement audiometry, play audiometry or pure tone audiometry depending on developmental age — before decisions about grommets are made.
Grommets (tympanostomy tubes)
ENT surgery
Small ventilation tubes inserted through the tympanic membrane to drain effusion and equalise middle ear pressure, typically extruding spontaneously after 6-12 months. Indications: persistent bilateral OME (usually 3+ months) with hearing loss and demonstrable functional impact on speech, language, learning or behaviour; recurrent AOM (commonly 3 episodes in 6 months or 4 in 12); OME in a child with additional risk such as Down syndrome, cleft palate, permanent hearing loss in the other ear, or visual impairment, where the threshold is lower. Effects on hearing are immediate but the benefit narrows over time as untreated effusions also resolve. Practical points: routine water precautions are no longer required for most children; otorrhoea through a grommet is treated with topical quinolone drops rather than oral antibiotics; and long-term risks include tympanosclerosis and persistent perforation in a small minority.
Cholesteatoma
ENT
Keratinising stratified squamous epithelium trapped within the middle ear or mastoid, forming an expanding sac of keratin debris that erodes bone through pressure and enzymatic activity. Acquired cholesteatoma usually arises from a retraction pocket driven by chronic Eustachian tube dysfunction; congenital cholesteatoma presents as a white mass behind an intact drum in a young child. Clinical hallmark: persistent, painless, foul-smelling otorrhoea that does not resolve, with an attic or posterosuperior retraction pocket. It is progressive and will not resolve medically. Untreated complications: conductive then sensorineural hearing loss from ossicular erosion, facial nerve palsy, labyrinthine fistula with vertigo, mastoiditis, meningitis and intracranial abscess. Management is surgical — tympanomastoid surgery with long-term surveillance or planned second-look for residual disease.
Eustachian tube dysfunction
ENT/Physiology
The underlying mechanism in most middle ear disease. The Eustachian tube ventilates the middle ear and equalises pressure; when it fails, negative middle ear pressure develops, causing retraction, transudation of fluid, and ultimately effusion, retraction pockets and cholesteatoma. Children are predisposed because their Eustachian tube is shorter, more horizontal and more compliant — which is why middle ear disease is fundamentally a paediatric problem that improves with craniofacial growth. Risk factors: upper respiratory infection; allergic rhinitis; adenoid hypertrophy; cleft palate and craniofacial syndromes; Down syndrome; passive smoking; and childcare attendance. IMPORTANT red flag: unilateral OME in an ADULT — particularly of South-East Asian or southern Chinese origin, or with neck lymphadenopathy or epistaxis — requires nasopharyngoscopy to exclude nasopharyngeal carcinoma obstructing the Eustachian tube.
Prevention of otitis media
Public health/Paediatrics
Several measures have good evidence. Pneumococcal conjugate vaccination reduces AOM caused by vaccine serotypes and, importantly, reduces complicated disease and mastoiditis; influenza vaccination modestly reduces AOM episodes. Breastfeeding is consistently protective, with effect increasing with duration and exclusivity. Avoidance of passive smoking is one of the strongest modifiable factors. Avoiding supine bottle feeding, and reducing dummy (pacifier) use beyond around 6-10 months, both reduce risk. In high-burden settings — including remote Indigenous populations where CSOM prevalence can exceed the WHO threshold defining a massive public health problem — additional measures matter: early identification through community ear health screening, treatment of persistent perforation, hearing support in schools, and reduction of household crowding and smoke exposure.

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