A single high-dose oral creatine supplement preserved cognitive performance by up to 12% during severe sleep deprivation in a small randomised trial, suggesting that the brain's energy crisis during fatigue can be partially mitigated by exploiting acute metabolic shifts that enhance creatine uptake across the blood-brain barrier. — Photo by Slumber Sleep Aid on Unsplash (Unsplash License)
MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.