Announcement: Why your brain hoards vitamin C: New evidence reveals its true role in stress and cognition

Last updated: 23/10/2026 13:26

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New evidence reveals vitamin C's primary role is not immune function but stress hormone synthesis. The brain prioritises vitamin C above all other organs, maintaining concentrations 200 times higher than blood plasma. — Photo by Rafael Minguet Delgado on Pexels (Pexels License)

Your brain concentrates vitamin C at 200× the level in your blood—but it's not for immune defence. New evidence shows vitamin C's real job: synthesizing cortisol and stress neurotransmitters. The brain retains 24% of vitamin C stores during deficiency while other organs collapse to 3%.

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GMJ Brief · Announcement

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ByProf. Giorgi Pkhakadze, MD, MPH, PhD

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MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.