Depression affects an estimated 280 million people worldwide, yet conventional treatment approaches often overlook nutritional factors that may exacerbate symptoms. Emerging research indicates that deficiencies in key micronutrients—B vitamins, vitamin D, magnesium, and zinc—are associated with impaired brain function and increased depressive symptom risk. These nutrients regulate neurotransmitter synthesis, support neuroprotection, and enhance the brain’s ability to manage oxidative stress.
However, experts emphasize a critical distinction: micronutrient deficiencies alone do not cause depression in most cases. Rather, nutritional insufficiency may worsen symptoms or contribute to treatment resistance in vulnerable individuals. A new analysis by the Georgian Medical Journal examines how micronutrient assessment can complement—not replace—evidence-based psychological interventions, pharmacotherapy, and lifestyle modifications in a holistic depression management strategy.
Read the full article on GMJ Newsroom.
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