Type: Rare cancer

Cholangiocarcinoma

Malignancy of the bile ducts, often diagnosed late.

Adrenocortical carcinoma

Aggressive cancer of the adrenal cortex, often hormonally active.

Chordoma

Slow-growing malignancy arising from notochord remnants along the axial skeleton.

Castleman disease

Lymphoproliferative disorder ranging from unicentric to multicentric inflammatory disease.

Ewing sarcoma

Aggressive bone/soft-tissue sarcoma of children and young adults.

Gastrointestinal stromal tumor

Mesenchymal tumor of the GI tract driven by KIT/PDGFRA mutations.

Diffuse intrinsic pontine glioma

Aggressive, inoperable pediatric brainstem glioma with very poor prognosis.

Erdheim-Chester disease

Rare non-Langerhans histiocytosis with multisystem xanthogranulomatous infiltration.