Tag: neurodegenerative disease
First Disease-Modifying Treatment Offers New Hope for Huntington’s Disease
A new disease-modifying therapy has shown the first measurable slowing of cognitive and motor decline in Huntington's disease, offering hope…
Kinesin: How cells’ tiniest molecular motors keep the body moving
Kinesin is a molecular motor protein that walks along microtubules, transporting essential cargo throughout cells. This nanoscale delivery system powers…
Yale researchers identify protein pathways driving Parkinson’s disease spread in the brain
Yale researchers have identified two neuron surface proteins that mediate the spread of alpha-synuclein, the toxic protein underlying Parkinson's disease.…
Roche Discontinues Huntington’s Gene-Silencing Program Amid Competitive Pressures
Roche has discontinued its Huntington's disease gene-silencing program, highlighting competitive pressures in neurodegenerative therapeutics. The decision comes as ARPA-H launches…
Tubulin offers new strategy to prevent toxic protein clumps in Alzheimer’s and Parkinson’s disease
Researchers at Baylor College of Medicine have identified tubulin as a cellular regulator that can redirect tau and alpha-synuclein proteins…
Experimental drug shows promise in protecting nerve cells from ALS damage
Researchers report that an experimental drug demonstrates neuroprotective properties in laboratory models of amyotrophic lateral sclerosis. The finding adds to…
Northwestern researchers identify cause of neuron overfiring in ALS and design potential treatment
Researchers at Northwestern Medicine's Les Turner ALS Center have identified the molecular mechanism driving neuronal hyperexcitability in ALS and designed…
University of Queensland Drug Targets Immune Receptor, Offering Hope for Motor Neuron Disease
Researchers at the University of Queensland have developed a novel drug that activates a previously difficult-to-target immune receptor, a breakthrough…