Tag: neuroinflammation
Yale researchers identify protein pathways driving Parkinson’s disease spread in the brain
Yale researchers have identified two neuron surface proteins that mediate the spread of alpha-synuclein, the toxic protein underlying Parkinson's disease.…
How Chronic Inflammation Blocks New Brain Cells: King’s College Study Reveals TNF-Alpha Pathway
Researchers at King's College London have discovered that TNF-alpha, a key inflammatory molecule, directly blocks the generation of new neurons…
BCG Vaccine Shows Promise in Reshaping Brain Immunity Against Alzheimer’s Disease
New research from Mass General Brigham investigators demonstrates that the BCG vaccine—routinely given to prevent tuberculosis—may reshape the brain's immune…
Foamy immune cells packed with fat may drive MS progression, new brain tissue study suggests
Researchers have discovered that immune cells packed with lipid droplets accumulate in the brains of patients with severe multiple sclerosis…
Beyond Neurons: How Brain’s Supporting Cells Drive Inflammation and Cognitive Resilience
The brain's health depends on more than neurons alone. A complex cellular ecosystem—astrocytes, microglia, and oligodendrocytes—orchestrates neural function through chemical…
Brain’s Support Cells Hold Key to Mental Health: How Astrocytes, Microglia, and Oligodendrocytes Shape Resilience
The human brain is far more than neurons alone. Astrocytes, microglia, and oligodendrocytes form a cellular network that determines whether…
Scientists Reprogram Brain Immune Cells to Combat Alzheimer’s Disease
Researchers have identified a molecule called OLE that restores protective function in brain immune cells in Alzheimer's disease models. The…
Blood Cancer Gene Mutations Trigger Alzheimer’s Disease Through Brain Inflammation
New research reveals blood cancer-associated genetic mutations in 43% of Alzheimer's patients, creating inflammatory brain cells that accelerate neurodegeneration. The…