Tag: TCA cycle

Mitochondrial TCA Cycle Intermediates Emerge as Master Regulators of Cellular Function Beyond Energy Production

Mitochondrial TCA cycle intermediates function as master regulators of epigenetic state, immune function, and tumor development, far beyond their role…

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Mitochondrial metabolism reshapes immunity, stem cells, and tumour development

Mitochondrial TCA cycle intermediates function as master regulators of immune responses, stem cell fate, and tumour development. Supporting mitochondrial health…

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Beyond Energy: How Mitochondrial Metabolites Control Immunity, Stem Cells, and Cancer Risk

Mitochondrial metabolites—acetyl-CoA, α-ketoglutarate, itaconate, succinate, and fumarate—function as master regulators of immune tolerance, stem cell fate, and tumor suppression, not…

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