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Newborn Health

GMJ News knowledge hub · last reviewed August 2026 · Georgian Medical Journal

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Newborns are the most vulnerable people on earth: approximately 2.3 million die in their first 28 days of life each year — now nearly half of all deaths in children under five — from conditions that are almost entirely preventable with known interventions (UNICEF 2023). The three leading killers — preterm birth complications, birth asphyxia and neonatal sepsis — share a common solution: skilled birth attendance, kangaroo mother care and immediate newborn care. The Every Newborn Action Plan (ENAP) targets ending preventable neonatal deaths by 2035.

Key messages

Most dangerous day
The first 28 days of life carry the highest mortality risk of any time in human existence. 2.3 million newborns die each year — 1 million on the very first day (UNICEF 2023).
47% of child deaths
Neonatal deaths account for 47% of all under-5 deaths globally — making newborn survival the frontier of child health progress.
Three killers, three solutions
Preterm birth, birth asphyxia and neonatal sepsis cause ~75% of neonatal deaths — all addressable with kangaroo mother care, immediate newborn care and clean delivery with antibiotics.
Kangaroo mother care — 36% mortality reduction
WHO's 2022 guidelines recommend initiating skin-to-skin kangaroo mother care immediately after birth for all small and preterm babies. Evidence shows 36% neonatal mortality reduction.
1.9M stillbirths invisible
1.9 million stillbirths occur annually — largely preventable with quality antenatal care and skilled birth attendance, yet almost entirely excluded from global health statistics and investment.
ENAP 2035 target
The Every Newborn Action Plan (ENAP), co-led by WHO and UNICEF, targets ending preventable neonatal deaths and stillbirths by 2035.

Key statistics

2.3M
neonatal deaths/year
UNICEF 2023
1M
on first day of life
UNICEF
47%
of all under-5 deaths
UN IGME 2023
1.9M
stillbirths/year
WHO/UNICEF 2023
36%
mortality reduction with KMC
WHO 2022
2035
ENAP target year
WHO/UNICEF

Neonatal mortality rate (per 1,000 live births) globally 2000-2022 — UN IGME

Source: UN Inter-agency Group for Child Mortality Estimation. Substantial but insufficient progress toward ENAP targets.

Glossary of key terms

Neonatal period
WHO
First 28 days of life — the highest-mortality period of human existence. Early neonatal (days 1-7) is most critical; the first 24 hours carries the greatest single-day risk.
Kangaroo mother care (KMC)
WHO 2022
Skin-to-skin care of small/preterm newborns by a parent, initiated immediately after birth. WHO 2022 guidelines recommend early initiation even for babies requiring medical care. Reduces mortality by up to 36%.
Preterm birth
WHO
Birth before 37 completed weeks — the leading cause of neonatal death globally. KMC substantially improves survival even at lower-resource facilities.
Birth asphyxia
WHO
Failure to initiate breathing at birth causing hypoxic brain injury. Causes ~25% of neonatal deaths. Basic neonatal resuscitation (bag-and-mask ventilation) is the life-saving response.
Neonatal sepsis
WHO
Bloodstream infection in first 28 days — fatal without prompt antibiotics. Early-onset from GBS/E. coli during delivery; late-onset often healthcare-acquired.
Stillbirth
WHO
Fetal death at or after 28 weeks. ~1.9M annually, 98% in LMICs. Largely excluded from health statistics despite being mostly preventable.

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About this hub. Produced by the GMJ News Editorial Team as a public-good service. Every statistic is linked to its primary source. Documents are preserved in the GMJ Repository with full attribution. Georgian Medical Journal · Contact the editorial team
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