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GMJ News > GMJ Briefs > The Cure Paradox: Why Gene Therapy Success Demands Financial Innovation

The Cure Paradox: Why Gene Therapy Success Demands Financial Innovation

GMJ
Last updated: 12/07/2026 18:43
By
Prof. Giorgi Pkhakadze
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1 Min Read
Medical professional reviewing gene therapy cost analysis and payment models on computer screen
Gene therapies costing up to $2 million per treatment face critical financing barriers despite proven therapeutic benefits. Healthcare economist calls for urgent payment infrastructure development to ensure patient access. — Photo by www.kaboompics.com on Pexels (Pexels License)
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1 min read|137 words

Medical science has achieved a remarkable milestone—gene therapies now offer potential cures for previously untreatable diseases. Yet a critical paradox threatens to undermine these breakthroughs: the healthcare system lacks the financial infrastructure to deliver them to patients.

According to health economist William Padula’s analysis, gene therapies costing up to $2 million per treatment have exposed fundamental weaknesses in how healthcare systems allocate resources. Traditional payment models evolved to manage recurring treatments and chronic disease management, not one-time curative interventions with unprecedented price tags.

Padula articulates the core challenge: “We do not lack cures. We lack the infrastructure to pay for and deliver them.” Healthcare organizations, payers, and policymakers must collaborate to develop innovative financing mechanisms that can bridge this critical gap and ensure equitable patient access to these life-saving treatments.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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