By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
GMJ NewsGMJ NewsGMJ News
  • Latest News
    • GMJ Briefs
  • The Wire
  • Health Topics
  • Podcast & Media
    • GMJ Audio
    • GMJ Videos
    • Podcast & Media
    • Podcast Episodes
  • GMJ Articles
    • Vol. 1 Issue 3 (2026)
    • Public Health Dictionary — Supplement Edition
    • IAP Legacy Series
    • Read Full Journal (gmj.ge) →
    • Pre-Launch Articles (2025)
    • Vol. 1 Issue 1 (2026)
    • Vol. 1 Issue 2 (2026)
  • Perspectives
    • Editorial
    • Explainers
    • Letters
    • Voices
  • Policy & Systems
    • Global Health
    • Health Policy
    • Migration & Health
    • Quality & Safety
    • Work & Health
  • Dictionary
    • Our Story: 20 Years in the Making
    • Browse A–Z
    • About the Project
    • Contribute a Term
  • Practice
    • Case Discussions
    • Clinical Updates
    • Pharmacy & Prescribing
  • Research Digest
    • Data & Numbers
    • Georgian Research
    • New Studies
  • Read the Journal →
Notification Show More
Font ResizerAa
GMJ NewsGMJ News
Font ResizerAa
  • Latest News
  • The Wire
  • Health Topics
  • Podcast & Media
  • GMJ Articles
  • Perspectives
  • Policy & Systems
  • Dictionary
  • Practice
  • Research Digest
  • Read the Journal →
  • Latest News
    • GMJ Briefs
  • The Wire
  • Health Topics
  • Podcast & Media
    • GMJ Audio
    • GMJ Videos
    • Podcast & Media
    • Podcast Episodes
  • GMJ Articles
    • Vol. 1 Issue 3 (2026)
    • Public Health Dictionary — Supplement Edition
    • IAP Legacy Series
    • Read Full Journal (gmj.ge) →
    • Pre-Launch Articles (2025)
    • Vol. 1 Issue 1 (2026)
    • Vol. 1 Issue 2 (2026)
  • Perspectives
    • Editorial
    • Explainers
    • Letters
    • Voices
  • Policy & Systems
    • Global Health
    • Health Policy
    • Migration & Health
    • Quality & Safety
    • Work & Health
  • Dictionary
    • Our Story: 20 Years in the Making
    • Browse A–Z
    • About the Project
    • Contribute a Term
  • Practice
    • Case Discussions
    • Clinical Updates
    • Pharmacy & Prescribing
  • Research Digest
    • Data & Numbers
    • Georgian Research
    • New Studies
  • Read the Journal →
Follow US
GMJ News > GMJ Briefs > The Chemical Foundation of Mental Health: Understanding Your Brain’s Neurotransmitter System

The Chemical Foundation of Mental Health: Understanding Your Brain’s Neurotransmitter System

GMJ
Last updated: 30/07/2026 15:30
By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
Share
1 Min Read
Diagram of neurotransmitter molecules and brain cell communication
Neurotransmitters—dopamine, serotonin, acetylcholine, and nine others—regulate mood, sleep, focus, and motivation through chemical signalling between brain cells. When this signalling becomes dysregulated, functional symptoms emerge before structural brain disease develops. — Photo by SHVETS production on Pexels (Pexels License)
SHARE
1 min read|124 words

Your capacity to concentrate, regulate emotion, sleep restfully, and maintain motivation hinges on a sophisticated system of chemical communication within the brain. Twelve major neurotransmitters—including dopamine, serotonin, acetylcholine, and GABA—orchestrate the signalling between brain cells that governs mood, cognition, and physiological function. When these chemical messengers operate in balance, mental resilience and cognitive clarity follow. However, dysregulation of neurotransmitter systems often produces functional symptoms such as mood disturbance, sleep disruption, and cognitive fog long before any structural brain pathology becomes detectable. This understanding underscores why early recognition of chemical imbalance is critical to mental health intervention. By appreciating the delicate equilibrium required for optimal brain function, individuals and clinicians can identify symptoms earlier and pursue targeted treatment strategies that restore neurochemical balance.

Was this article helpful?

GMJ Brief · Announcement

📰 Read the full article: How neurotransmitters control your mood, sleep, and focus: a primer on brain chemistry →

Related reference
  • Choline · Ingredient
  • GABA · Ingredient
Share This Article
Facebook Whatsapp Whatsapp LinkedIn Telegram Bluesky Copy Link Print
GMJ
ByProf. Giorgi Pkhakadze, MD, MPH, PhD
Follow:
MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.

Submit Your Paper →

Georgia's peer-reviewed open-access medical journal. No APC until January 2027.
Submit Manuscript →
L-Arginine’s Hidden Role: From Vascular Function to Alzheimer’s Protein Dynamics

L-arginine extends its biological influence far beyond vascular regulation into unexpected domains:…

Omega-3 Supplement Oxidation: Separating Controversy from Clinical Evidence

Omega-3 supplement oxidation is measurable in laboratories but clinical evidence of human…

Folic Acid Prevents Neural Tube Defects in 36% of Cases: Evidence Contradicts ‘Gene Test’ Claims

Folic acid supplementation has achieved a documented 36% reduction in neural tube…

Submit Your Paper to GMJ

No APC until January 2027.
Submit Manuscript →

You Might Also Like

Scientific researchers working on longevity interventions in laboratory setting

XPRIZE Invests $101 Million in Global Race for Age Reversal Innovations

By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
05/06/2026
Medical illustration of bispecific antibody targeting cancer cells

Dual-Pathway Immunotherapy BNT327 Demonstrates Clinical Activity in Treatment-Resistant Lung Cancer

By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
11/06/2026
Bar chart showing reduction in non-heme iron absorption from black tea, peppermint, cocoa, and chamomile beverages

Black Tea Blocks 94% of Iron Absorption—But One Simple Fix Restores It

By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
31/07/2026
Healthcare professional in clinical setting processing distant conflict trauma

Brain on Alert: New Data Shows How Distant Conflict Activates Healthcare Workers’ Threat Response

By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
16/07/2026
Facebook Twitter Youtube Instagram
Company
  • Privacy Policy
  • Accreditation Canada in Georgia
  • GMJ Journal
  • Submit Manuscript
  • Editorial Team
  • Register at GMJ

Subscribe to GMJ News — Click here

Join Community
© 2026 Georgian Medical Journal (GMJ). Published by the Public Health Institute of Georgia (PHIG). All rights reserved.
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?