By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
GMJ NewsGMJ NewsGMJ News
  • Latest News
    • GMJ Briefs
  • Podcast & Media
    • Podcast Episodes
    • GMJ Audio
    • GMJ Videos
  • Research Digest
    • New Studies
    • Georgian Research
    • Data & Numbers
  • Policy & Systems
    • Health Policy
    • Quality & Safety
    • Migration & Health
    • Global Health
  • Practice
    • Clinical Updates
    • Case Discussions
    • Pharmacy & Prescribing
    • Ingredients A-Z
  • Perspectives
    • Editorial
    • Explainers
    • Voices
    • Letters
  • Health Topics
  • GMJ Articles
    • Vol. 1 Issue 2 (2026)
    • Vol. 1 Issue 1 (2026)
    • Pre-Launch Articles (2025)
  • Read the Journal →
  • About GMJ News
Notification Show More
Font ResizerAa
GMJ NewsGMJ News
Font ResizerAa
  • Latest News
    • GMJ Briefs
  • Podcast & Media
    • Podcast Episodes
    • GMJ Audio
    • GMJ Videos
  • Research Digest
    • New Studies
    • Georgian Research
    • Data & Numbers
  • Policy & Systems
    • Health Policy
    • Quality & Safety
    • Migration & Health
    • Global Health
  • Practice
    • Clinical Updates
    • Case Discussions
    • Pharmacy & Prescribing
    • Ingredients A-Z
  • Perspectives
    • Editorial
    • Explainers
    • Voices
    • Letters
  • Health Topics
  • GMJ Articles
    • Vol. 1 Issue 2 (2026)
    • Vol. 1 Issue 1 (2026)
    • Pre-Launch Articles (2025)
  • Read the Journal →
  • About GMJ News
Follow US
GMJ News > GMJ Briefs > Announcement: How Gut Dysbiosis Triggers Systemic Inflammation: A Mechanistic Overview

Announcement: How Gut Dysbiosis Triggers Systemic Inflammation: A Mechanistic Overview

GMJ
Last updated: 13/08/2026 21:29
By
Prof. Giorgi Pkhakadze
Share
0 Min Read
Diagram showing pathways from dysbiosis through intestinal barrier dysfunction to systemic organ inflammation
When the gut microbiota becomes imbalanced, reduced production of short-chain fatty acids weakens the intestinal barrier, allowing bacterial toxins to enter the bloodstream and trigger systemic inflammation affecting metabolism, hormones, and multiple organ systems. — Photo by AI25.Studio Studio on Pexels (Pexels License)
SHARE
1 min read|44 words

When gut dysbiosis reduces beneficial bacteria, the intestinal barrier weakens—allowing bacterial toxins into the bloodstream and triggering systemic inflammation across adipose tissue, liver, pancreas, and brain. Explore the mechanistic pathway from dysbiosis to whole-body metabolic dysfunction.

Read the full article on GMJ Newsroom →

Was this article helpful?

GMJ Brief · Announcement

📰 Read the full article: How Gut Dysbiosis Triggers Systemic Inflammation: A Mechanistic Overview →

Share This Article
Facebook LinkedIn Bluesky Copy Link Print
GMJ
ByProf. Giorgi Pkhakadze
Follow:
Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

Submit Your Paper →

Georgia's peer-reviewed open-access medical journal. No APC until January 2027.
Submit Manuscript →
UK childhood vaccination coverage holds steady at high levels, latest quarterly data shows

The UK's Cover of Vaccination Evaluated Rapidly (COVER) programme reports sustained high…

EMA Launches Email Notifications for Clinical Trial Information System

The European Medicines Agency has rolled out email notification subscriptions in CTIS,…

Independent Inquiry Finds Systemic Racism in Maternity Care Undermines Patient Safety

An independent inquiry has documented systemic racism and discrimination affecting patient safety…

Submit Your Paper to GMJ

No APC until January 2027.
Submit Manuscript →

You Might Also Like

SITUATION BRIEF: Bundibugyo Ebola Outbreak, Democratic Republic of Congo

By
Prof. Giorgi Pkhakadze
31/05/2026
Digital blood pressure monitor with smartphone showing health data transmission

Digital Home Blood Pressure Monitoring Emerges as Game-Changer in Cardiovascular Prevention

By
Prof. Giorgi Pkhakadze
03/07/2026
Mitochondrial cell illustration representing energy metabolism benefits of PQQ supplementation

Clinical Data: PQQ Shows Dose-Dependent Effects Across Cognitive and Metabolic Markers

By
Prof. Giorgi Pkhakadze
08/08/2026
WHO Essential Medicines List timeline 1977-2025 showing continuity in core medications

Announcement: Forty-eight years of WHO essential medicines: core drugs unchanged since 1977

By
Prof. Giorgi Pkhakadze
07/08/2026
Facebook Twitter Youtube Instagram
Company
  • Privacy Policy
  • Contact US
  • GMJ Journal
  • Submit Manuscript
  • Editorial Team
  • Register at GMJ
  • Terms of Use

Subscribe to GMJ News — Click here

Join Community
© 2026 Georgian Medical Journal (GMJ). Published by the Public Health Institute of Georgia (PHIG). All rights reserved.
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?

Not a member? Sign Up