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GMJ News > GMJ Briefs > Study of 308 Cardiac Surgery Patients Shows 25% Opioid Reduction with Nerve Block Intervention

Study of 308 Cardiac Surgery Patients Shows 25% Opioid Reduction with Nerve Block Intervention

GMJ
Last updated: 12/06/2026 23:19
By
Prof. Giorgi Pkhakadze
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1 Min Read
Medical illustration showing regional nerve block procedure for cardiac surgery pain management
A multicentre randomised trial shows bilateral nerve blocks with ropivacaine reduce opioid consumption by 25% after cardiac surgery. The EPOCH CardioLink-10 study demonstrates improved pain management with enhanced safety profiles. — Photo: Anna Shvets / Pexels
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1 min read|116 words

A double-blind, placebo-controlled trial has provided robust evidence for the efficacy of regional anaesthesia in cardiac surgery pain management. The multicentre study enrolled 308 adults and measured cumulative morphine equivalent doses in the first 48 hours post-operatively. Patients receiving bilateral SPIP blocks with ropivacaine demonstrated a 25% reduction in opioid consumption compared to the placebo group. Additionally, time to extubation improved significantly in the intervention cohort, with patients regaining respiratory independence faster than controls. Pain scores at 24 hours also favoured the nerve block group, with mean ratings of 3.2 versus 4.8 on a numerical pain rating scale. These quantifiable improvements suggest regional anaesthesia warrants consideration as a standard component of cardiac surgery pain protocols. Read the full article on GMJ Newsroom.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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