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GMJ News > GMJ Briefs > 55 Million Global Dementia Cases Drive Urgency for Novel Alzheimer’s Therapies

55 Million Global Dementia Cases Drive Urgency for Novel Alzheimer’s Therapies

GMJ
Last updated: 13/06/2026 10:30
By
Prof. Giorgi Pkhakadze
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1 Min Read
Scientific illustration of CBD molecules and brain neurons showing reduced inflammation
New preclinical research suggests CBD may help fight Alzheimer's disease by reducing neuroinflammation in mouse models. The study found that inhaled CBD significantly reduced key inflammatory markers in the brain. — Photo: Nataliya Vaitkevich / Pexels
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1 min read|126 words

The global dementia burden underscores the critical need for innovative treatment approaches. According to the World Health Organization, 55.2 million people worldwide currently live with dementia, with Alzheimer’s disease accounting for approximately 70 percent of cases—roughly 38.9 million individuals. Most significantly, 16.3 million lack access to effective treatment options.

New preclinical research offers potential hope through cannabidiol (CBD), which demonstrated anti-inflammatory effects in mouse models of Alzheimer’s disease. By reducing microglial activation and neuroinflammatory markers, CBD may address a fundamental mechanism underlying cognitive decline.

These findings are particularly significant given the limited therapeutic options available. As the global population ages, the demand for disease-modifying treatments will intensify, making research into emerging compounds like CBD increasingly important for addressing this public health crisis.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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