The Lancet Global Health reports that while oral pre-exposure prophylaxis (PrEP) uptake has reached record levels, current coverage remains significantly below WHO targets. As of 2023, 3.5 million people globally received PrEP at least once, with over 75% (2.6 million) in the African region. However, experts note this falls substantially short of the 2025 global target of 10 million PrEP users.
The commentary highlights that PrEP represents one of the decade’s major public health successes, with modelling data confirming both effectiveness and cost-efficiency in sub-Saharan African epidemics. The expansion of biomedical HIV prevention has fundamentally shifted prevention strategies, particularly for high-risk populations requiring accessible, risk-informed approaches.
Health authorities must now redesign service delivery mechanisms to bridge the gap between current coverage and 2025 targets. The focus shifts toward improving access infrastructure, reducing barriers to initiation, and strengthening retention across affected regions. This is a developing story.
Source: [Comment] Redesigning service delivery for the next phase of HIV…
Was this article helpful?


