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GMJ News > GMJ Briefs > Key Finding: Breaking sedentary patterns may lower cancer mortality risk, UK study suggests

Key Finding: Breaking sedentary patterns may lower cancer mortality risk, UK study suggests

GMJ
Last updated: 29/09/2026 15:26
By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
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Chart showing cancer mortality hazard ratios for prolonged versus interrupted sedentary behavior and physical activity replacement effects.
A study of 91,292 UK participants found that each additional hour of prolonged uninterrupted sitting increased cancer mortality risk by 9%, while breaking up sitting with light or moderate activity significantly reduced that risk. — "nurse pushing a patient in a wheelchair" by franchiseopportunitiesphotos is licensed under CC BY-SA 2.0. To view a copy of this license, visit https://creativecommons.org/licenses/by-sa/2.0/. (CC BY-SA 2.0)
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Each extra hour of prolonged sitting = 9% higher cancer mortality risk. But replacing 30 min with moderate activity = 8% lower risk. Breaking the sitting habit matters.

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GMJ Brief · Key Finding

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ByProf. Giorgi Pkhakadze, MD, MPH, PhD
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MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.

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