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GMJ News > GMJ Briefs > Key Finding: Eli Lilly’s Gene Editor Cuts Cholesterol 62% in First Human Trial

Key Finding: Eli Lilly’s Gene Editor Cuts Cholesterol 62% in First Human Trial

GMJ
Last updated: 03/07/2026 08:26
By
Prof. Giorgi Pkhakadze
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Medical illustration showing gene editing targeting PCSK9 for cholesterol reduction
Eli Lilly's experimental gene-editing therapy VERV-102 achieved a 62% reduction in cholesterol levels at the highest dose in Phase 1 clinical trials. The single-dose treatment targets the PCSK9 gene to potentially provide permanent cholesterol control. โ€” Photo by Supplements On Demand on Pexels (Pexels License)
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๐Ÿ“Š 62% cholesterol reduction achieved with Lilly's VERV-102 gene editor in Phase 1 trials. Single-dose treatment could replace daily medications.

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GMJ Brief ยท Key Finding

๐Ÿ“ฐ Read the full article: Eli Lillyโ€™s Gene Editor Cuts Cholesterol 62% in First Human Trial โ†’

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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