Chronic graft-versus-host disease represents a major quality-of-life concern for allogeneic hematopoietic cell transplant recipients, affecting nearly one-third to one-half of this patient population within the first two years following transplantation. A comprehensive analysis published in Nature Reviews Disease Primers (June 2026) underscores the critical importance of systematic screening protocols that span multiple organ systems, including skin, oral mucosa, gastrointestinal tract, liver, and pulmonary tissues. The review identifies that early detection and intervention can significantly prevent irreversible organ damage and functional decline. Clinical management requires coordinated multidisciplinary approaches tailored to individual patient risk profiles, emphasizing that comprehensive screening is not merely diagnostic but therapeutic in nature. These evidence-based protocols are now recognized as essential components of post-transplant care standards. Read the full article on GMJ Newsroom.
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