Nature Medicine, Published online: 15 September 2026; doi:10.1038/s41591-026-04559-4In a phase 1 trial evaluating GFH375, an oral, dual onβoff binding KRAS G12D inhibitor, in patients with KRASG12D-mutated solid tumors, there was one treatment-related death, while most treatment-related adverse events were low-grade, and encouraging response rates were observed in non-small cell lung cancer and pancreatic cancer.
This is a developing story.
Source: Oral KRAS G12D inhibitor GFH375 for previously treated advanced solidβ¦
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