As the World Organisation for Animal Health assesses progress toward UN commitments, three key investment gaps emerge as barriers to effective AMR control. First, global funding mechanisms fail to match the scale of political declarations, leaving national action plans underfunded across human, animal, and environmental sectors. Second, the One Health approach—essential for integrated AMR response—requires coordinated investment that currently remains fragmented across independent health systems.
Third, regional infrastructure deficits in low- and middle-income countries perpetuate vulnerability to antimicrobial resistance. Without sustained investment in veterinary services, laboratory diagnostics, and surveillance capabilities, these regions cannot implement evidence-based stewardship programmes. Healthcare stakeholders and policymakers must recognize that closing these gaps demands not just political commitment, but concrete financial allocation and cross-sector collaboration to prevent the projected escalation of AMR-related mortality and economic burden.
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