Type: Skin
Epidermolysis bullosa
Group of disorders with extreme skin fragility and blistering from minor trauma; severe types cause scarring and SCC risk.
Generalized pustular psoriasis
Severe systemic pustular variant of psoriasis with flares of widespread sterile pustules and fever.
Cutaneous T-cell lymphoma
Indolent-to-aggressive lymphoma of skin-homing T cells presenting with patches, plaques and tumors.
Hidradenitis suppurativa
Chronic inflammatory disease of apocrine-bearing skin with painful nodules, abscesses and sinus tracts.
Ichthyosis
Heritable disorders of cornification with persistent scaling skin.
Netherton syndrome
Severe ichthyosiform disorder with hair-shaft defect and atopy.
Pemphigus vulgaris
Autoimmune blistering disease with intraepidermal acantholysis affecting skin and mucosa.
Xeroderma pigmentosum
Defective nucleotide-excision repair with extreme UV sensitivity and very high skin cancer risk.
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