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Adding pirtobrutinib to venetoclax-rituximab improves survival in relapsed chronic lymphocytic leukemia

Adding the BTK inhibitor pirtobrutinib to venetoclax-rituximab significantly improves progression-free survival in patients with relapsed or refractory chronic lymphocytic leukemia,…

Long-term antihypertensive therapy shows diminishing cardiovascular benefits, meta-analysis of 51 trials reveals

A meta-analysis of 51 randomized trials in Nature Medicine reveals that cardiovascular benefits from antihypertensive therapy plateau rather than compound…

BCG Vaccine Shows Promise in Reshaping Brain Immunity Against Alzheimer’s Disease

New research from Mass General Brigham investigators demonstrates that the BCG vaccine—routinely given to prevent tuberculosis—may reshape the brain's immune…

Annual NHS Screening Recommended for Women with PCOS to Improve Care and Early Detection

The UK's National Institute for Health and Care Excellence recommends annual NHS health checks for women with polycystic ovary syndrome…

Men’s suicide rates remain stubbornly high despite mental health interventions—evidence points to targeted approaches

Despite public health efforts to address men's mental health, suicide mortality among men remains persistently high, according to an editorial…

Molecular Tumor Boards Show Promise in Bridging Precision Oncology’s Access Gap

A meta-analysis in PLOS Medicine shows that molecular tumor boards—multidisciplinary teams interpreting genomic data—improve precision oncology outcomes. But resource constraints…

Engineered T Cells Show Promise in Hard-to-Treat Children’s Brain Tumors

A phase 1 trial published in Nature Medicine demonstrates that engineered T cells targeting multiple tumor antigens are well tolerated…

GLP-1 medications reduce deaths and amputations in type 2 diabetes with peripheral artery disease

New research published in the Journal of the American Heart Association shows GLP-1 receptor agonist medications reduce deaths, amputations, and…

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