Tag: drug safety
ACE Inhibitors and Angioedema: Why Distinguishing Drug Types Matters for Treatment
ACE inhibitors can cause two distinct forms of angioedema with different treatment requirements. Bradykinin-mediated cases do not respond to standard…
UK Health Regulator Issues Class 4 Alert for Denosumab Injection Labelling Error
MHRA issues Class 4 alert for Ponlimsi denosumab after Teva UK reports carton labelling error stating "For application to the…
UK Medicine Broker Registry Updated to Strengthen Drug Supply Chain Oversight
UK MHRA has updated its public register of authorised medicine brokers, strengthening oversight of pharmaceutical intermediaries. The registry provides transparency…
Popular Anti-Aging Drug Combination Causes Severe Brain Damage in Mice
A widely researched anti-aging drug combination caused severe brain damage in mice, including myelin loss and cognitive changes resembling "chemo…
UK Medicines Regulator Suspends Multiple Drug Manufacturing Licences
UK's medicines regulator has suspended and revoked multiple pharmaceutical manufacturing licences for quality failures. The enforcement actions target companies failing…
FDA Official Who Questioned COVID Vaccines and Antidepressants Exits Amid Regulatory Shifts
A senior FDA official known for questioning COVID-19 vaccine safety profiles and antidepressant efficacy claims has departed the agency, highlighting…
First-Trimester NSAIDs and Birth Defects: Large Cohort Study Finds No Increased Risk
A population-based cohort study of 54,000 pregnancies found no increased risk of major congenital malformations associated with first-trimester NSAID exposure,…