Tag: PARP inhibitors

Scientific illustration showing DNA repair mechanisms being disrupted in cancer cells
New StudiesResearch Digest

Scientists Disrupt Cancer Cell DNA Repair to Overcome Drug Resistance

New research shows UNI418 compound can disrupt cancer cell DNA repair mechanisms, making drug-resistant tumors vulnerable to treatment. Combined with…

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GMJ Research Desk
Medical illustration showing prostate cancer treatment targeting multiple pathways
New StudiesResearch Digest

Triple-Drug Therapy Extends Survival in Advanced Prostate Cancer Trial

Triple-drug combination therapy significantly improved survival outcomes in advanced prostate cancer trial. The approach combines PARP inhibition with androgen-signaling blockers…

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GMJ Research Desk
Diagram showing genomic instability pathway leading to cancer treatment resistance
New StudiesResearch Digest

Genomic instability fuels cancer resistance through newly identified cellular pathway

New research reveals how genomic instability in ovarian cancer activates the STING-WNT pathway, creating protective myofibroblasts that drive both immune…

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GMJ Research Desk

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