Tag: supplementation
Magnesium Form Matters Less Than Consistent Intake for Brain Health, Evidence Suggests
New evidence shows that magnesium's cognitive benefits depend on total intake, not on which commercial salt form you choose. Head-to-head…
How Your Gut Controls Magnesium Absorption: The TRPM6 Channel and What Form Actually Matters
Your gut's TRPM6 ion channels regulate magnesium absorption based on body status, upregulating when depleted and downregulating when replete. While…
Magnesium Supplementation Reduces Blood Pressure: Meta-Analysis Shows Modest but Measurable Benefits
A 2024 umbrella meta-analysis shows that magnesium supplementation at doses of 400 mg or more, taken for at least 12…
Creatine and Kidney Damage: What the Evidence Actually Shows
A 2025 systematic review of 21 studies and analysis of 685 clinical trials confirms that creatine supplementation does not damage…
The B-Vitamin Methylation Triad: How B12, Folate, and B6 Work Together in Cardiovascular and Neurological Health
B12, folate, and B6 form an integrated metabolic system supporting DNA synthesis, homocysteine regulation, and neurological function. Current RDA levels…
Why creatine works in muscle but not the brain—yet
Creatine supplementation raises muscle creatine by 20–50% in days, but brain creatine increases by only 4% due to the blood–brain…
PQQ Shows Consistent Benefits for Inflammation, Energy, and Memory in Human Trials
Human clinical studies document consistent benefits of pyrroloquinoline quinone (PQQ) supplementation on inflammation, energy metabolism, and memory—with effects emerging at…
Magnesium and Heart Disease: What the Evidence Actually Shows
A meta-analysis of 40 population studies involving over one million people found no evidence that magnesium prevents overall cardiovascular disease,…