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GMJ News > GMJ Briefs > Millennium of Traditional Use Now Supported by Modern Hair Follicle Research

Millennium of Traditional Use Now Supported by Modern Hair Follicle Research

GMJ
Last updated: 26/06/2026 11:41
By
Prof. Giorgi Pkhakadze
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1 Min Read
Traditional Chinese medicinal herbs and modern laboratory equipment representing convergence of ancient and contemporary medicine
Traditional Chinese herb Polygonum multiflorum shows promise for treating androgenetic alopecia through multiple mechanisms including hormone blocking and follicle protection. Laboratory studies suggest the millennium-old remedy aligns with modern hair biology understanding. — Photo by RDNE Stock project on Pexels (Pexels License)
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1 min read|130 words

Polygonum multiflorum, known as He Shou Wu in traditional Chinese medicine, boasts over 1,000 years of documented use for hair and scalp health—a historical precedent now receiving scientific validation. Contemporary ethnopharmacological research has identified why this ancient remedy may be effective for androgenetic alopecia treatment.

Laboratory investigations reveal the herb’s mechanism of action mirrors modern pharmacological approaches: it blocks DHT production by inhibiting 5α-reductase, the same enzyme targeted by prescription finasteride. Beyond hormone modulation, studies demonstrate additional benefits including activation of hair growth signaling pathways and follicle protection mechanisms.

This data-driven validation of traditional wisdom represents a significant development in natural medicine research, suggesting that historical medical practices warrant rigorous scientific scrutiny. The findings support further clinical investigation into Polygonum multiflorum as a complementary approach to conventional androgenetic alopecia treatments.

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Related reference
  • Finasteride · Drug
  • He Shou Wu · Ingredient
  • SAMe · Ingredient
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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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