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GMJ News > GMJ Briefs > What You Need to Know About Vitamin K: Three Critical Insights on Bone Health and Nutritional Hierarchy

What You Need to Know About Vitamin K: Three Critical Insights on Bone Health and Nutritional Hierarchy

GMJ
Last updated: 25/08/2026 21:29
By
Prof. Giorgi Pkhakadze
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Diagram showing vitamin K allocation hierarchy from liver clotting factors to extrahepatic bone and arterial proteins
Current vitamin K dietary guidelines prioritise blood clotting at the expense of bone and arterial health, leaving proteins critical for long-term vascular and skeletal integrity approximately 30% undercarboxylated in otherwise healthy adults, according to triage theory research. — Photo by Marta Branco on Pexels (Pexels License)
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1 min read|123 words

New research clarifies how your body allocates vitamin K and what this means for long-term health. Here are three essential takeaways:

First, current recommendations (90–120 mcg daily) prioritise clotting function while leaving bone and arterial tissues partially starved of fully activated vitamin K-dependent proteins. Second, achieving complete carboxylation of bone-building proteins likely requires substantially higher intakes: greater than 1 mg/day of K1 or approximately 200 mcg/day of MK-7 (K2).

Third, the form of vitamin K matters significantly. While K1 circulates only 1–1.5 hours, MK-7 remains bioavailable for 3–4 days, enabling superior tissue distribution and extrahepatic activation. These insights suggest that individuals concerned with bone density and cardiovascular health may benefit from discussing vitamin K intake strategies with healthcare providers.

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📰 Read the full article: Vitamin K’s Hidden Hierarchy: Why Your Body Prioritises Blood Clotting Over Bone Health →

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  • Vitamin K · Ingredient
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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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