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GMJ News > GMJ Briefs > Announcement: Vitamin C May Reverse Skin Aging at the Genetic Level, New Research Suggests

Announcement: Vitamin C May Reverse Skin Aging at the Genetic Level, New Research Suggests

GMJ
Last updated: 13/08/2026 13:29
By
Prof. Giorgi Pkhakadze
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Microscopic image of aged human skin cells showing epidermal thinning before and after vitamin C treatment, illustrating gene expression changes
New research in The Journal of Investigative Dermatology reveals that vitamin C may reverse skin aging by altering gene expression in aged skin cells through DNA demethylation. Topical formulations (10–20% L-ascorbic acid) appear more effective than oral supplements for reaching epidermal stem cells. — Photo by Яна Костюкевич on Pexels (Pexels License)
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1 min read|47 words

Breaking: Vitamin C may reverse skin aging at the genetic level. New research in The Journal of Investigative Dermatology shows vitamin C enhances gene expression linked to epidermal thickening through DNA demethylation. Topical formulations (10–20%) appear more effective than oral supplements.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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