Announcement: Why creatine works in muscle but not the brain—yet

ბოლო განახლება: 04/08/2026 13:29

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Creatine supplementation raises muscle creatine by 20–50% in days, but brain creatine increases by only 4% due to the blood–brain barrier. A meta-analysis of 16 randomised controlled trials found cognitive improvements in stressed or fatigued populations, but evidence in healthy people remains sparse. — Photo by Alex Saks on Unsplash (Unsplash License)

1 min read|50 words

New analysis: why creatine works brilliantly for muscle (20–50% rise in days) but struggles to reach the brain (4% rise with standard dosing). The blood–brain barrier changes everything. Meta-analysis shows cognitive benefits mainly in stressed, sleep-deprived populations—not healthy people. Read the full breakdown.

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ავტორი:Prof. Giorgi Pkhakadze

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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

Announcement: Why creatine works in muscle but not the brain—yet

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