Seventy percent of autoimmune diseases affect women, yet these conditions remain significantly under-researched in traditional clinical trials—a stark illustration of gender disparities in medical science. This research gap reflects broader patterns of women’s exclusion from medical studies, perpetuating limited understanding of how diseases uniquely impact women across their lifespans. Wearable health technologies present a compelling solution by enabling continuous, objective monitoring in real-world settings rather than controlled laboratory environments. Through constant data collection, these devices can reveal disease patterns and physiological responses that conventional research methodologies miss. The comprehensive review in Nature Reviews Disease Primers emphasizes how wearables could fill critical knowledge voids by tracking hormonal influences, disease progression, and treatment responses across diverse populations of women. This technological advancement offers researchers unprecedented opportunities to generate sex-specific evidence and improve clinical outcomes.
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