A striking new finding from ongoing cancer research demonstrates that men taking high-dose vitamin B12 supplements exceeding 55 micrograms daily for over a decade exhibit three to four times higher lung cancer rates compared to non-users. This statistic represents one of the most significant adverse associations yet documented for supplement overuse.
The data comes from meta-analyses spanning multiple observational studies and challenges the safety profile previously attributed to water-soluble B12. Researchers suggest this elevated risk may result from B12’s role in cellular proliferation—while adequate levels support healthy DNA synthesis, excessive amounts may paradoxically promote tumor development in susceptible populations.
These findings underscore the importance of maintaining B12 within optimal physiological ranges rather than pursuing supraphysiological levels through supplementation. Read the full article on GMJ Newsroom.
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