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GMJ News > GMJ Briefs > NEJM Documents Rare ‘Black Esophagus’ Case: Why Clinicians Must Know This Gastrointestinal Emergency

NEJM Documents Rare ‘Black Esophagus’ Case: Why Clinicians Must Know This Gastrointestinal Emergency

GMJ
Last updated: 25/06/2026 18:26
By
Prof. Giorgi Pkhakadze
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Endoscopic view showing black esophageal mucosa characteristic of acute esophageal necrosis
A rare case of acute esophageal necrosis documented in NEJM highlights the critical need for early recognition of this life-threatening "black esophagus" condition. The distinctive circumferential black discoloration on endoscopy defines this gastrointestinal emergency. — Bi-lingual Clinical Trial Consultation (45067326622).jpg by NIAID / CC BY 2.0 via Wikimedia Commons (CC BY 2.0)
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1 min read|125 words

A striking case report in the New England Journal of Medicine has renewed focus on acute esophageal necrosis, commonly referred to as ‘black esophagus’ for its distinctive endoscopic appearance. This rare but life-threatening condition presents with circumferential black discoloration of the esophageal mucosa, typically affecting the distal esophagus and halting abruptly at the gastroesophageal junction.

The condition results from a complex interplay of ischemic injury, acid reflux, and compromised mucosal defense mechanisms. Clinicians must recognize that early endoscopic identification is paramount to improving patient outcomes and preventing serious complications including perforation and stricture formation. The case underscores the critical importance of maintaining high clinical suspicion in high-risk populations, particularly elderly patients with multiple comorbidities, cardiovascular disease, or diabetes.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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