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GMJ News > GMJ Briefs > Skin-Roasted Peanuts Show Promise for Cerebral Perfusion in Older Adults

Skin-Roasted Peanuts Show Promise for Cerebral Perfusion in Older Adults

GMJ
Last updated: 05/08/2026 05:29
By
Prof. Giorgi Pkhakadze, MD, MPH, PhD
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Infographic showing 4% improvement in cerebral blood flow from daily peanut consumption compared to 10-year aging decline
A new study in Clinical Nutrition (2025) found that consuming 60 grams of skin-roasted peanuts daily improved global brain blood flow by 4% in older adults—equivalent to reversing 10 years of age-related cognitive decline. The effect appears mediated by arginine, an amino acid that enhances nitric-oxide–driven vascular dilation. — Photo by Pixabay on Pexels (Pexels License)
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1 min read|130 words

A clinical intervention study published in Clinical Nutrition (2025) has identified a simple dietary strategy for supporting brain health in aging populations. Researchers found that consuming 60 grams of skin-roasted peanuts daily improved global cerebral blood flow by approximately 4% in older adult participants. This modest but meaningful improvement is physiologically equivalent to reversing roughly 10 years of age-related cognitive decline in cerebral perfusion.

The mechanism underlying this benefit appears to centre on arginine, a semi-essential amino acid present in peanuts at concentrations of 1.8–2.0 grams per serving. Arginine serves as a substrate for nitric oxide synthesis, triggering vasodilation in cerebral vessels and enhancing oxygen delivery to brain tissue. The findings suggest that targeted dietary interventions may offer a practical, evidence-based approach to maintaining cognitive function during aging.

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ByProf. Giorgi Pkhakadze, MD, MPH, PhD
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MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.

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