Astrocytes, comprising roughly 50% of brain cells, are now recognised as active global regulators of brain state rather than passive support cells. They influence alertness, stress response, and motivation by modulating neural networks without requiring structural rewiring—a paradigm shift reshaping neuroscience and psychiatric disease understanding. — "Astrocytes" by NICHD NIH is licensed under CC BY 2.0. To view a copy of this license, visit https://creativecommons.org/licenses/by/2.0/. (CC BY 2.0)
MD, MPH, PhD. Editor-in-Chief, Georgian Medical Journal (GMJ). Professor and Head, School of Public Health, David Tvildiani Medical University (DTMU), Tbilisi, Georgia. Chair, Public Health Institute of Georgia (PHIG). President, Accréditation Sans Frontières (ASF), Paris. Secretary/Treasurer, UEMS Section of Public Health. WHO Consultant, Health and Migration, Geneva. Former Member, UN Secretary-General's Independent Accountability Panel for Every Woman, Every Child, Every Adolescent (IAP-EWEC, 2016–2021). ORCID: 0000-0001-7609-4515.