CAR T cell therapy targets mutant calreticulin in myelofibrosis: new hope for precision cancer immunotherapy
A new CAR T cell therapy engineered to target mutant calreticulin successfully depleted disease-driving cells in myelofibrosis xenografts and human…
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Correction issued for GDP-mannose immunotherapy study in triple-negative breast cancer
Science Translational Medicine has issued a formal erratum for a July 2026 research article on guanosine diphosphate–mannose as a potential…
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USC researchers identify enzyme target for reducing Alzheimer’s brain inflammation
USC researchers have identified a new approach to combat Alzheimer's by targeting the cPLA2 enzyme that drives brain inflammation. The…
Ceramide Metabolism May Explain Racial Disparities in Prostate Cancer Drug Response
New research reveals that differences in ceramide lipid metabolism between Black and white men may explain racial disparities in prostate…
Wearable Ultrasound Patch for High-Risk Pregnancies Shows Promise in UC San Diego Trial
UC San Diego engineers develop wearable ultrasound patch for continuous fetal monitoring during high-risk pregnancies. The device maintains consistent imaging…
Rare Earth Mining Creates Hidden Public Health Crisis in Myanmar
Rare earth mining operations in Myanmar are creating an unmonitored environmental health crisis as global demand for these critical minerals…
Language Barriers in Healthcare: How Communication Gaps Affect Patient Safety and Quality of Care
Language barriers in healthcare contribute to 25% of medical errors in multicultural settings, affecting patient safety and diagnostic accuracy. Professional…
New Clinical Guidelines Address Heart-Brain Multimorbidity Management
New clinical practice guidelines published in CMAJ provide evidence-based recommendations for managing patients with concurrent cardiovascular and neurological conditions. The…
Eli Lilly’s Gene Editor Cuts Cholesterol 62% in First Human Trial
Eli Lilly's experimental gene-editing therapy VERV-102 achieved a 62% reduction in cholesterol levels at the highest dose in Phase 1…
Beta Blockers After Heart Attack Show No Benefit in Major International Study
A major international study of over 5,000 patients found beta blockers provide no benefit after uncomplicated heart attacks, with women…