Tag: immunotherapy
Combination immunotherapy with radiation shows promise in hormone-receptor-positive breast cancer
A randomized phase 2 trial in Nature Medicine demonstrates that combining durvalumab immunotherapy with stereotactic radiation produces encouraging clinical responses…
NHS Expands Access to Pembrolizumab for Advanced Cervical Cancer
The NHS has approved pembrolizumab, an immune checkpoint inhibitor, for hundreds of women with advanced cervical cancer. The drug enhances…
FDA-Approved Drug Restores Immunotherapy Efficacy in Rare Liver Cancer by Releasing Trapped T Cells
Researchers have identified that rare liver cancers evade immunotherapy by trapping immune T cells in fibrous tissue. An FDA-approved drug…
Immune ‘Peacemakers’ May Unlock Long-Term Disease Remission in Autoimmune Conditions
Regulatory immune cells that suppress harmful inflammation could unlock long-term disease remission in autoimmune and neurodegenerative conditions by restoring immune…
Correction issued for MAGE-A4/A8 immunotherapy trial in advanced solid tumours
Nature Medicine has published an author correction to a phase 1 trial investigating MAGE-A4/MAGE-A8-targeted T cell engager therapy in patients…
Scientists Reprogram Brain Immune Cells to Combat Alzheimer’s Disease
Researchers have identified a molecule called OLE that restores protective function in brain immune cells in Alzheimer's disease models. The…
Combination Immunotherapy Shows Promise in Bladder Cancer Surgery: New NEJM Evidence
Combination enfortumab vedotin and pembrolizumab administered perioperatively shows emerging promise in muscle-invasive bladder cancer, according to new clinical correspondence in…
CAR T Cells Show Promise Against Smoldering Myeloma, But Patient Selection Is Critical
CAR T cell therapy achieves deep remissions in smoldering myeloma, a precancerous blood disorder, but induces severe toxicities in approximately…