HomeTopics › Indoor Air Quality

Indoor Air Quality

GMJ News knowledge hub · last reviewed August 2026 · Georgian Medical Journal

SummaryStatisticsGlossaryGMJ newsFAQDocumentsOrganizationsResearch

People in high-income settings spend around 90% of their time indoors, and the indoor environment carries both the world’s deadliest confirmed air hazard and some of its most contested new ones. The settled core is enormous: household air pollution from cooking with solid fuels kills roughly 3.2 million people a year, radon is the second leading cause of lung cancer after smoking, second-hand tobacco smoke kills over a million annually, and damp and mould demonstrably worsen asthma. The contested frontier is narrower than headlines suggest — gas stoves genuinely raise indoor nitrogen dioxide and are associated with childhood asthma, but the widely quoted claim that they cause one in eight US childhood asthma cases rests on modelling assumptions that are actively disputed; meanwhile ozone-generating “air purifiers” are marketed as a solution while adding a regulated pollutant to the room (WHO household air pollution fact sheet).

Key messages

SETTLED AND ENORMOUS: household air pollution from solid fuels
The deadliest indoor air problem attracts the least Western attention: roughly 2.1 billion people cook with wood, charcoal, crop waste, dung or coal on open fires and rudimentary stoves, and the resulting household air pollution kills about 3.2 million people a year — pneumonia in children, COPD, ischaemic heart disease, stroke and lung cancer in adults — with women and children bearing the exposure. Clean cooking transition (LPG, electricity, genuinely clean biomass stoves) is among the highest-value interventions in global health, and it dwarfs every contested indoor air question in high-income countries combined.
SETTLED: radon, second-hand smoke, damp and mould
Three further indoor exposures are beyond scientific dispute. Radon — a natural radioactive soil gas accumulating in buildings — is the second cause of lung cancer after smoking and the first among never-smokers, with risk multiplicative in smokers; testing is cheap and mitigation established. Second-hand tobacco smoke kills over a million people yearly and has no safe level — the evidence base behind smoke-free laws, among the most successful health policies ever enacted. And damp and mould consistently associate with asthma development and exacerbation, an exposure concentrated in poor-quality housing and therefore as much a housing-policy issue as a medical one.
GENUINELY CONTESTED: gas stoves — real exposure, disputed magnitude
Gas combustion indoors demonstrably produces nitrogen dioxide at concentrations that can exceed outdoor air standards in unventilated kitchens, and meta-analyses have long associated gas cooking with childhood asthma (a 2013 synthesis estimated over 30% higher odds). The 2022 claim that 12.7% of US childhood asthma is attributable to gas stoves — the number that ignited the political firestorm — applied that older meta-analysis through a population attributable fraction model whose assumptions (causality, transferability, exposure equivalence) are actively disputed, and a large Swedish cohort found no association. The defensible summary: the hazard is real, ventilation is the confirmed remedy, and the headline attributable fraction is a modelling estimate presented with more confidence than it earned.
OPEN AND POST-PANDEMIC: ventilation as infrastructure
COVID-19 converted ventilation from an engineering afterthought into public health policy: recognition of airborne transmission produced the first standards explicitly targeting infection risk (ASHRAE 241 in 2023), national clean-air-in-buildings initiatives and a research agenda on CO2 monitoring as a ventilation proxy. The open questions are economic and normative rather than mechanistic — how much ventilation, at what energy cost, mandated where — because the underlying science (dilution reduces far-field airborne transmission) is established. Indoor air is plausibly the pandemic's most durable public health legacy, and the one least implemented so far.
UNSUPPORTED AND SOMETIMES HARMFUL: the air-cleaning marketplace
The consumer response to indoor air anxiety includes genuinely effective technology and outright harm sold side by side. HEPA filtration demonstrably removes particles and reduces allergen and smoke exposure, with growing trial evidence for health endpoints; ventilation and source control outperform any gadget. Meanwhile ozone-generating 'purifiers' add a regulated lung irritant to the room by design; ionisers and 'plasma' devices can generate ozone and secondary pollutants with thin efficacy data; and houseplants, at any realistic density, do approximately nothing to indoor VOCs — a myth descended from a NASA chamber study misapplied to real rooms. The market rewards the sensation of purification over the removal of pollutants.
THE FRAME: buildings are a health determinant, unequally distributed
People in high-income countries spend about 90% of life indoors, and indoor air integrates every upstream inequity: damp, crowding, gas cooking without ventilation, traffic-adjacent housing, no air conditioning in heatwaves and no filtration in wildfire smoke — which now episodically makes indoor air in affected regions worse than a bad day in any megacity. The gradient runs the same direction globally as locally: the poorest breathe the worst indoor air, from dung smoke in rural kitchens to mould in social housing. Treating indoor air as infrastructure — building codes, housing standards, school ventilation — rather than as consumer self-protection is where the evidence points and the disparities close.

Key statistics

3.2 million
deaths per year from household air pollution, overwhelmingly from cooking with solid fuels
WHO
2.1 billion
people still relying on polluting fuels and technologies for cooking
WHO/IEA
#2
radon’s rank among causes of lung cancer — first among never-smokers; 3-14% of lung cancers by country
WHO
1.2 million+
annual deaths attributed to second-hand smoke exposure — no safe level exists
WHO
12.7%
the contested modelled share of US childhood asthma attributed to gas stoves — an estimate, not a measurement
Gruenwald et al. 2022
~90%
share of time spent indoors in high-income countries — the case for treating buildings as a health determinant
Exposure science

Indoor air — where the disagreement actually lies

Source: Bars show strength of supporting evidence. High values indicate well-supported propositions; low values indicate claims tested and not supported.

Glossary of key terms

Household air pollution and the energy ladder
Global health
The 'energy ladder' runs from dung and crop residues through wood and charcoal to kerosene, LPG, biogas and electricity, with indoor emissions falling by orders of magnitude on the climb. Burning solid fuel indoors produces PM2.5 at concentrations that can exceed WHO guideline values a hundred-fold, and the exposure is structured by gender and age — women cooking and infants carried beside the fire. WHO defines clean cooking by emission performance rather than fuel identity, and the disappointing trial history of 'improved' biomass cookstoves (real emission cuts, largely unrealised health gains in trials such as HAPIN) has shifted the field toward genuinely clean fuels — making clean cooking access, tracked under SDG 7, the pragmatic frontline of indoor air.
Radon: testing and mitigation
Environmental health
Radon is a decay product of uranium in soil and rock — an odourless radioactive gas that seeps through foundations and concentrates indoors, with enormous variation between neighbouring buildings. Its alpha-emitting progeny lodge in airway epithelium; pooled European case-control studies established lung cancer risk rising about 16% per 100 Bq/m³ long-term exposure with no evident threshold, and the smoker-radon combination is multiplicative. WHO recommends a 100 Bq/m³ reference level. The public health frustration is that everything works and little happens: testing costs little, sub-slab depressurisation reliably cuts concentrations, yet testing rates stay low even in mapped high-radon zones — a pure implementation failure.
Nitrogen dioxide and the gas stove evidence
Evidence
Gas flames fix atmospheric nitrogen into NO2, an airway irritant with established respiratory effects from outdoor pollution science, and kitchen measurements confirm unvented gas cooking can push indoor NO2 past one-hour outdoor standards. The association with childhood asthma appeared in meta-analysis a decade before the controversy — the 2013 synthesis reporting roughly 32% higher odds — but individual studies conflict (a large Swedish cohort found no association), exposure varies enormously with ventilation and stove use, and causality versus correlated housing factors remains arguable. The 12.7% attributable fraction that dominated headlines multiplied the older meta-analytic odds ratio through gas-stove prevalence — methodologically standard, assumption-laden, and defensible only with the uncertainty attached, which the ensuing culture war removed in both directions.
Volatile organic compounds and formaldehyde
Exposure science
Indoor VOC concentrations typically run several-fold above outdoor levels, emitted by building materials, furnishings, paints, adhesives, cleaning products and fragrances — with formaldehyde (a Group 1 carcinogen at occupational exposures, released by composite wood products) the best characterised. Established effects at typical home concentrations are mainly irritant and inconsistently linked to asthma; the honest position is that chronic low-level mixture effects are under-studied rather than exonerated. Practical control is source-side and cheap: low-emission certified materials, airing new furnishings, moderate use of fragranced products, ventilation during and after painting — a hierarchy in which buying a VOC-sensing gadget ranks last.
Ventilation metrics: ACH, CO2 and ASHRAE 241
Engineering
Ventilation is measured in air changes per hour (ACH) or litres per second per person; occupant-generated CO2 serves as a convenient proxy for how much exhaled air accumulates — outdoors ~420 ppm, well-ventilated rooms under ~800, stuffy classrooms often far beyond. COVID-19 produced the first standard written for infection risk: ASHRAE 241 (2023) defines equivalent clean airflow targets per occupant for infection-risk-management mode, combinable from outdoor air, filtration (MERV-13 and above) and validated air cleaning including far-UVC. The unresolved tension is energy: every litre of conditioned outdoor air costs carbon, which is why heat-recovery ventilation and filtration-heavy strategies dominate serious retrofit designs.
Wildfire smoke and the indoor refuge problem
Climate/Health
Climate-driven wildfire seasons have created a recurring inversion: regions with historically clean air experiencing weeks when outdoor PM2.5 exceeds hazardous thresholds and the official advice is 'stay indoors' — which only helps if indoors is actually cleaner. Leaky buildings without filtration converge toward outdoor concentrations within hours; homes with recirculating HVAC on MERV-13 filters or portable HEPA units maintain PM2.5 at small fractions of outdoor levels, and the do-it-yourself box-fan filter (Corsi-Rosenthal) performs respectably in published tests for tens of dollars. Smoke readiness — filtration capacity, sealed rooms, N95s for unavoidable outdoor time — is becoming a standard preparedness domain alongside heat, and access to it tracks income precisely.

Latest GMJ coverage

Air Pollutants Alter Brain Activity and Lung Function Within Four Hours
27/05/2026
PFAS ‘Forever Chemicals’ Persist in Ski Wax Rooms Despite Regulatory Bans
08/07/2026
Protecting Children During Extreme Heat: Clinical Guidance for Families and Healthcare Providers
09/08/2026
Close Contact Alone May Not Drive Influenza Transmission, Controlled Study Suggests
27/07/2026
Vitamin D Insufficiency Affects Up to 97% in Some Regions—Here’s What the Evidence Shows
24/07/2026
World Cup Mass Gatherings Create High-Risk Environment for Infectious Disease Transmission
17/06/2026

Frequently asked questions 12 Q&A — structured for Google featured snippets and AI discovery

Knowledge hub: guidelines, conventions and reports

Organizations working in migration and health

Related health topics

Air pollutionAsthmaCOPDLung cancerTobaccoClimate change and health

About this hub. Produced by the GMJ News Editorial Team as a public-good service. Every statistic is linked to its primary source. Documents are preserved in the GMJ Repository with full attribution. Georgian Medical Journal · Contact the editorial team