Announcement: Single protein discovery could unlock CAR-T cell therapy’s full potential

GMJ
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Prof. Giorgi Pkhakadze
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Scientific illustration showing CAR-T cells attacking cancer with molecular pathway highlighted
Researchers identify NFIL3 protein as key barrier to CAR-T cell therapy success. Disabling this protein maintained stronger cancer-fighting activity in preclinical models. โ€” Photo: turek / Pexels
1 min read|39 words

๐Ÿงฌ Breakthrough discovery: Single protein NFIL3 identified as major barrier to CAR-T cell therapy success. When disabled, engineered immune cells maintained cancer-fighting power longer in preclinical studies. This could transform cancer immunotherapy durability.

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GMJ
ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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