Mitochondrial TCA cycle intermediates function as master regulators of epigenetic state, immune function, and tumor development, far beyond their role in energy production. Strategic support through exercise, nutrition, and targeted supplements maintains metabolic signaling capacity. — Photo by Blue Bird on Pexels (Pexels License)
Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.