High-fat, low-fibre diets, food additives, and irregular eating patterns damage the gut barrier through three converging mechanisms: reduced short-chain fatty acid production, mucus layer thinning, and circadian desynchronisation. These changes drive low-grade inflammation linked to obesity, diabetes, and cardiovascular disease. — Photo by 女子 正真 on Pexels (Pexels License)
Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.
