A comprehensive analysis published in Nature Reviews Disease Primers highlights wearable health technologies as a transformative solution to long-standing gender disparities in medical research and clinical care. Women have been systematically excluded from clinical trials and research protocols, creating substantial knowledge gaps in understanding how diseases manifest across sexes. Wearable devices offer a groundbreaking approach by enabling continuous, real-world data collection outside traditional laboratory settings. These technologies can capture physiological variations throughout menstrual cycles, pregnancy, and menopause—periods historically excluded from research protocols. The National Institutes of Health has increasingly recognized the importance of sex-specific research, yet implementation remains limited in conventional study designs. By providing unprecedented insights into women’s health patterns, wearables could fundamentally reshape personalized healthcare delivery and close decades-long research gaps.
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