Tag: preclinical research
Neurotensin Receptor 2 Activation Shows Promise in Preventing Heart Failure Progression
Activation of neurotensin receptor 2 in preclinical models significantly reduced pathological changes in heart tissue, suggesting a novel therapeutic target…
Novel Prime-and-Pull Vaccine Strategy Shows Promise Against Genital Herpes in Preclinical Models
Yale researchers developed a novel prime-and-pull vaccine that prevented genital herpes infection in preclinical models, potentially addressing a 30-year gap…
Post-exercise brain signal may be key to fitness gains, mouse study suggests
Researchers at Jackson Laboratory and University of Pennsylvania identified brain neurons that appear necessary for endurance training to produce fitness…
Scientists Reprogram Brain Immune Cells to Combat Alzheimer’s Disease
Researchers have identified a molecule called OLE that restores protective function in brain immune cells in Alzheimer's disease models. The…
Mammals May Possess Hidden Regenerative Capacity: Scientists Redirect Healing Toward Tissue Regrowth Instead of Scarring
Scientists have demonstrated that mammals may retain dormant regenerative abilities through a two-stage treatment approach that redirects wound healing away…
New Drug Target for Alzheimer’s Shows Promise in Preclinical Studies
Researchers identified a novel Alzheimer's mechanism and developed an experimental compound that slowed nerve cell loss in mouse models. The…
Single protein discovery could unlock CAR-T cell therapy’s full potential
Researchers identify NFIL3 protein as key barrier to CAR-T cell therapy success. Disabling this protein maintained stronger cancer-fighting activity in…
CBD Shows Promise in Reducing Alzheimer’s-Related Brain Inflammation
New preclinical research suggests CBD may help fight Alzheimer's disease by reducing neuroinflammation in mouse models. The study found that…