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Meningitis

GMJ News knowledge hub · last reviewed August 2026 · Georgian Medical Journal

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Meningitis can kill within 24 hours of symptom onset: it causes an estimated 238,000 deaths per year, and 1 in 5 survivors has lasting disability — hearing loss, brain damage or limb loss from septicaemia (WHO). Effective vaccines exist against the leading bacterial causes — meningococcal, pneumococcal and Hib — and have transformed the epidemiology in vaccinated populations. The WHO Defeating Meningitis by 2030 roadmap targets a 70% reduction in deaths and elimination of bacterial meningitis epidemics.

Key messages

Kills in hours
Bacterial meningitis can kill within 24 hours — every hour of antibiotic delay increases mortality by 7-10%. It is one of the few infectious diseases where speed is measured in hours not days.
Defeat Meningitis 2030
WHO's roadmap (WHA73) targets: eliminating bacterial meningitis epidemics; reducing vaccine-preventable cases by 50% and deaths by 70%; improving survivor quality of life.
Vaccines work
Effective vaccines exist against the main bacterial causes: meningococcal (A, B, C, W, Y), pneumococcal and Hib. MenAfriVac eliminated group A epidemic meningitis from the African meningitis belt.
1 in 5 survivors disabled
~20% of bacterial meningitis survivors have permanent disability — most commonly sensorineural hearing loss (affects 30% of pneumococcal meningitis survivors).
Non-blanching rash is an emergency
A purpuric (non-blanching) rash in a febrile patient signals meningococcal septicaemia — a medical emergency requiring immediate antibiotics. Absence does not exclude meningococcal disease.
Viral meningitis is different
Viral meningitis — mainly from enteroviruses — is far more common than bacterial and generally self-limiting. It does not require antibiotics. Laboratory distinction is essential.

Key statistics

2.5M
meningitis cases/year
WHO
238K
meningitis deaths/year (2019)
WHO/GBD
1 in 5
survivors with lasting disability
WHO
50%
reduction in bacterial cases targeted 2030
WHA73
70%
reduction in deaths targeted 2030
WHA73
24hrs
can be fatal from symptom onset
WHO

Meningitis deaths globally (thousands) 2000-2019 — GBD/WHO

Source: Global Burden of Disease / WHO. Decline driven by PCV and Hib vaccination scale-up.

Glossary of key terms

Bacterial meningitis
WHO
Most severe form — mainly from N. meningitidis, S. pneumoniae and Hib. Fatal without immediate antibiotics. Mortality 10-15% even with treatment; sequelae in ~20% of survivors.
N. meningitidis
WHO/ECDC
Meningococcal bacteria — carried harmlessly in throats of 10-35% of people; occasionally invades causing meningitis and/or rapidly fatal septicaemia. Vaccines for groups A, B, C, W and Y.
Non-blanching rash
WHO/Clinical
Purpuric rash not fading under glass pressure — indicates meningococcal septicaemia with blood vessel damage. A medical emergency.
MenAfriVac
WHO/MVP
Meningococcal group A conjugate vaccine at $0.40/dose — effectively eliminated group A epidemic meningitis in the African meningitis belt from 2010.
Sensorineural hearing loss
WHO
Most common sequela of bacterial meningitis — affects ~30% of pneumococcal meningitis survivors. Audiological evaluation should follow all bacterial meningitis cases in children.
Lumbar puncture
WHO/Clinical
Definitive diagnostic test — CSF analysis distinguishing bacterial (high cells, high protein, low glucose, bacteria on Gram stain) from viral meningitis.

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Related health topics

VaccinesChild healthSepsisAMRPneumoniaNewborn health

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