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GMJ News > GMJ Briefs > New Data Highlights Vaccine Effectiveness Gap: Why Enhanced Formulations Matter

New Data Highlights Vaccine Effectiveness Gap: Why Enhanced Formulations Matter

GMJ
Last updated: 29/06/2026 06:17
By
Prof. Giorgi Pkhakadze
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1 Min Read
Medical professional preparing enhanced flu vaccine for older adult patient
UK regulators approve enhanced flu vaccine with adjuvant for adults 50+, designed to boost immune response in older adults where standard vaccines show reduced effectiveness. — Photo by www.kaboompics.com on Pexels (Pexels License)
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1 min read|114 words

Recent vaccine effectiveness studies reveal a stark disparity in influenza protection across age groups. Adults aged 18-49 achieve 65% vaccine effectiveness, while those aged 50-64 see protection drop to 45%, and adults 65 and older experience only 25% effectiveness with standard vaccines. This substantial decline underscores why enhanced formulations are medically necessary.

The newly approved UK adjuvanted trivalent flu vaccine directly targets this protection gap by stimulating stronger immune responses in older adults. Evidence from the Centers for Disease Control and Prevention confirms that adjuvanted vaccines significantly improve effectiveness in populations over 65. This regulatory approval represents a data-driven solution to a well-established clinical challenge, potentially improving health outcomes for millions of older UK residents during annual flu seasons.

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ByProf. Giorgi Pkhakadze
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Prof. Giorgi Pkhakadze, MD, MPH, PhD, is Editor-in-Chief of the Georgian Medical Journal and Chair of the Public Health Institute of Georgia (PHIG). He is Professor and Head of the Department of Social and Behavioural Sciences at David Tvildiani Medical University, and Secretary/Treasurer of the UEMS Section of Public Health. ORCID: 0000-0001-7609-4515.

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