Tag: Parkinson’s disease
Vitamin D Controls Dopamine Production in Parkinson’s-Vulnerable Brain Cells
Vitamin D receptors inside dopamine-producing neurons in the substantia nigra control genes regulating dopamine synthesis and neuronal survival, according to…
Yale researchers identify protein pathways driving Parkinson’s disease spread in the brain
Yale researchers have identified two neuron surface proteins that mediate the spread of alpha-synuclein, the toxic protein underlying Parkinson's disease.…
Tubulin offers new strategy to prevent toxic protein clumps in Alzheimer’s and Parkinson’s disease
Researchers at Baylor College of Medicine have identified tubulin as a cellular regulator that can redirect tau and alpha-synuclein proteins…
Pesticide Chlorpyrifos Linked to More Than Double Risk of Parkinson’s Disease, UCLA Study Finds
Researchers at UCLA have found that long-term exposure to the pesticide chlorpyrifos approximately doubles the risk of Parkinson's disease, with…
How Brain-Spine Circuits Control Walking—And Why They Fail First in Aging and Parkinson’s Disease
Walking relies on integrated brain-spine circuits controlling posture, balance, and rhythm. New evidence shows aging and Parkinson's disease preferentially damage…
Adaptive Deep Brain Stimulation Restores Walking in Parkinson’s Disease: Nature Medicine Study
A new study in Nature Medicine demonstrates that deep brain stimulation devices using real-time neural decoding algorithms can significantly improve…
First Dual-Target Gene Therapy for Parkinson’s Disease Shows Promise in Early Trial
First-in-human trial of BBM-P002 dual-target gene therapy shows sustained 12-month motor improvements in Parkinson's disease patients with excellent safety profile.…
Orthostatic Hypotension in Parkinson’s Disease: New Clinical Practice Guidelines
New clinical guidelines address orthostatic hypotension, which affects up to 70% of Parkinson's patients. Evidence-based recommendations emphasize systematic screening and…