Tag: Parkinson’s disease

How Brain-Spine Circuits Control Walking—And Why They Fail First in Aging and Parkinson’s Disease

Walking relies on integrated brain-spine circuits controlling posture, balance, and rhythm. New evidence shows aging and Parkinson's disease preferentially damage…

Adaptive Deep Brain Stimulation Restores Walking in Parkinson’s Disease: Nature Medicine Study

A new study in Nature Medicine demonstrates that deep brain stimulation devices using real-time neural decoding algorithms can significantly improve…

First Dual-Target Gene Therapy for Parkinson’s Disease Shows Promise in Early Trial

First-in-human trial of BBM-P002 dual-target gene therapy shows sustained 12-month motor improvements in Parkinson's disease patients with excellent safety profile.…

Orthostatic Hypotension in Parkinson’s Disease: New Clinical Practice Guidelines

New clinical guidelines address orthostatic hypotension, which affects up to 70% of Parkinson's patients. Evidence-based recommendations emphasize systematic screening and…

Gut microbiome screening could predict Parkinson’s disease risk years before symptoms emerge

New research published in Nature Medicine reveals that gut microbiome analysis could identify Parkinson's disease risk years before symptoms appear.…

Blocking Key Protein GPNMB Shows Promise in Halting Parkinson’s Disease Spread

Scientists have identified GPNMB, a protein that helps Parkinson's disease spread through the brain by creating a destructive cycle between…

Multi-arm platform trials could revolutionize neurological disease research

Platform trials could test 15-20 neurological treatments per decade compared to 3-5 using traditional methods. New Lancet commentary argues this…

New PET Tracer Successfully Detects Alpha-Synuclein in Living Brains for Parkinson’s Diagnosis

Revolutionary PET tracer [11C]MODAG-005 successfully detects alpha-synuclein protein aggregates in living brains, offering breakthrough potential for early Parkinson's disease diagnosis…