Explainers

Plain-language deep dives for public audiences

Can laughter improve health? Researchers launch study to find out

A new research initiative called the Laughter Lab is systematically investigating whether laughter can improve health and wellbeing. The study…

Submit Your Paper →

Georgia's peer-reviewed open-access medical journal. No APC until January 2027.

More form Explainers

How the body metabolises alcohol: the biochemistry behind why drinks linger

Alcohol metabolism is a three-step enzymatic pathway that generates toxic acetaldehyde and depletes NAD⁺ cofactors,…

How glycine lowers core body temperature to trigger sleep—a thermostat mechanism

Glycine triggers sleep by lowering core body temperature through activation of the suprachiasmatic nucleus and…

How Creatine Actually Works: The ATP Shuttle System Explained

Creatine supplementation does not work primarily through water retention or caffeine-like stimulation. Instead, it enhances…

Why higher zinc supplement doses don’t deliver proportionally more absorption

Zinc supplements marketed at 30mg, 50mg, or higher doses deliver far less additional absorbed zinc…

Why DHA Is Not a Brain Supplement—It’s Brain Architecture

DHA is not a brain supplement—it is a fundamental structural component of brain tissue, comprising…