Explainers

Plain-language deep dives for public audiences

Hypertension’s Hidden Complexity: Why One-Size-Fits-All Treatment Fails

Hypertension is not a single disease but a clinical manifestation of dysregulation across five distinct physiological systems: fluid retention, kidney…

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Georgia's peer-reviewed open-access medical journal. No APC until January 2027.

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Mitochondria as cellular decision-makers: reframing disease, aging, and inflammation

Mitochondria regulate far more than energy production—they control inflammation, ageing, and disease progression through metabolic…

How testosterone is really made: the brain–gonad feedback loop explained

Testosterone production is regulated by a precise feedback loop between the brain and testes, not…

L-Theanine: How an amino acid shifts brain waves toward calm focus without drowsiness

L-theanine, a naturally occurring amino acid in green tea, shifts brain electrical activity toward patterns…

How Muscle Contractions Signal the Brain: The Myokine Pathway Explained

Skeletal muscle releases signalling molecules called myokines that travel through the bloodstream to regulate learning,…

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